Yeah, but, I don’t see how that really changes anything.
On a smaller instance (or one that’s defederated from others … in either direction), that might very well completely shift focuses.
For the Fediverse specific community, if you want one with the most chance of getting to the developers, use the instance that they’re on, otherwise, I’d think to just let the cultures develop and diverge naturally as they’re likely to.
From what I understand due to the way that Lemmy handles federation, it doesn’t (currently?) have a way to handle an instance changing its domain name and still being able to communicate or even an individual user changing their instance and retaining their comments/votes/etc… (this might be more ActivityPub limited since the way Mastodon does it still seems pretty hacky and just a work around for underlying issues).
From a website perspective, yeah, just change some settings and you’re good to go and accessible on the web, but that doesn’t mean that anything regarding Lemmy is going to actually work.